IminemĀ® is a sterile preparation of imipenem and cilastatin sodium. Imipenem is a broad
spectrum antibiotic which belongs to carbapenem class of antibiotics. It has the ability to kill
a wide variety of bacteria. It works by interfering with their ability to form cell walls, and
therefore the bacteria break up and die. Imipenem, the active antibiotic ingredient, is
partially inactivated by an enzyme in the kidney which can reduce its effectiveness.
Therefore it is combined with cilastatin sodium which blocks the effect of this enzyme.
Cilastatin sodium does not have any antibacterial effects and does not affect the
antibacterial activity of the imipenem.
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